Privacy Preference Centre
When you visit any website, the website may obtain or store information in your browser, usually through the use of cookies. This information may be about you, your preferences or your device, and is primarily used to make the site work as intended. Generally, the information does not directly identify you, but can provide you with a more personalised web experience. Because we respect your right to privacy, you may choose not to allow us to use certain cookies. Click on the individual category headings to learn more and to change our default settings. However, blocking some types of cookies may affect your experience on the site and the services we can offer.
More information
Manage consent preferences
- Technical Cookies Always active
They are those that allow the user to navigate through a website, platform or application and the use of the different options or services that exist in it, for example, control traffic and data communication, identify the session, access restricted access parts, remember the elements that make up an order, make the buying process of an order, make the application for registration or participation in an event, use security features while browsing, store content for broadcasting videos or sound or share content through social networks.
- tube Cookies
If you accept them, we will be able to show YouTube videos that appear on the website.
- Cookies de análisis o medición
Son aquellas que permiten al responsable de las mismas, el seguimiento y análisis del comportamiento de los usuarios de los sitios web a los que están vinculadas. La información recogida mediante este tipo de cookies se utiliza en la medición de la actividad de los sitios web, aplicación o plataforma y para la elaboración de perfiles de navegación de los usuarios de dichos sitios, aplicaciones y plataformas, con el fin de introducir mejoras en función del análisis de los datos de uso que hacen los usuarios del servicio.
Reject all Confirm my preferences

Biocan provides intelligent solutions in Animal Health

Teléfono+34 960 089 726 / +34 657 01 38 82
Artro K-nan
I need more information about this product
Contain natural extracts
What are its active ingredients?
Chondroitin and glucosamine [2] are essential molecules for the biosynthesis of chondrocytes, the cells that make up cartilage tissue. They are essential for keeping joints hydrated and thus maintaining their flexibility and elasticity.

Glycine and proline [3] are amino acid precursors of collagen, a protein found in the tissues of skin, bones, ligaments, tendons and cartilage. Collagen provides flexibility, elasticity and strength to joints.

Zinc, together with vitamins C and E,[4] protect joints from damage caused by reactive oxygen species, i.e. they act as antioxidants. In addition, recent studies have shown that vitamin C stimulates collagen biosynthesis.

Hyaluronic acid [5] is an essential biomolecule for water binding in many tissues, including cartilage tissue. Keeping joints hydrated helps to keep them smooth, elastic and flexible. In the joints, it acts as a lubricant, reducing friction and promoting shock absorption. It also reduces the death of chondrocytes, stimulates the biosynthesis of proteoglycans which inhibit the expression of pro-inflammatory mediators and interacts with the nerve endings present in the joint, exerting an analgesic effect.

Boswellia serrata [6] is a tree native to India which is widely used in traditional medicine for the treatment of osteoarthritis and other inflammatory processes. Recent studies in rats with collagen-induced osteoarthritis show that Boswellia Serrata extract was able to inhibit pro-inflammatory mediators, preventing degradation of cartilage collagen.

Curcuma longa [7] is an herbaceous plant from southwest India traditionally used as a spice or natural colouring agent. Several trials in animal models of arthritis show that dried extracts of Curcuma Longa help to reduce joint inflammation by protecting chondrocytes from the catabolic effect of pro-inflammatory cytokines.

Harpagofito prucumbens,[8] better known as "Devil's Claw", is a natural herbaceous plant from southern Africa that belongs to the Pedaliaceae family. Several in vitro studies have shown that the dry extract of Harpagofito Prucumbens has chondroprotective activity, as they have shown a reduction in the synthesis of pro-inflammatory mediators and inhibition of enzymes responsible for collagen degradation. In addition, there are known trials attributing analgesic properties to the dry extract of Harpagofito Prucumbens, although the mechanism remains unknown.

How much does each tablet provide?

[1] Moreau, M., Lussier, B., Pelletier, J. P., Martel-Pelletier, J., Bédard, C., Gauvin, D., & Troncy, E. (2014). A medicinal herb-based natural health product improves the condition of a canine natural osteoarthritis model: a randomized placebo-controlled trial. Research in veterinary science, 97(3), 574–581. https://doi.org/10.1016/j.rvsc.2014.09.011
[2] Blanco, F. J., Camacho-Encina, M., González-Rodríguez, L., Rego-Pérez, I., Mateos, J., Fernández-Puente, P., Lourido, L., Rocha, B., Picchi, F., Silva-Díaz, M. T., Herrero, M., Martínez, H., Verges, J., Ruiz-Romero, C., & Calamia, V. (2019). Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis. Therapeutic advances in chronic disease, 10, 2040622319870013. https://doi.org/10.1177/2040622319870013
[3] de Paz-Lugo, P., Lupiáñez, J. A., & Meléndez-Hevia, E. (2018). High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis. Amino acids, 50(10), 1357–1365. https://doi.org/10.1007/s00726-018-2611-x
[4] Alalwan T. A. (2022). Nutraceuticals and their role in promoting musculoskeletal healthy aging. Annali di igiene : medicina preventiva e di comunita, 10.7416/ai.2022.2552. Advance online publication. https://doi.org/10.7416/ai.2022.2552
[5] Dai, W. L., Lin, Z. M., Guo, D. H., Shi, Z. J., & Wang, J. (2019). Efficacy and Safety of Hylan versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis. The journal of knee surgery, 32(3), 259–268. https://doi.org/10.1055/s-0038-1641142
[6] Sethi, V., Garg, M., Herve, M., & Mobasheri, A. (2022). Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis. Therapeutic advances in musculoskeletal disease, 14, 1759720X221124545. https://doi.org/10.1177/1759720X221124545
[7] Henrotin, Y., Dierckxsens, Y., Delisse, G., Maes, N., & Albert, A. (2022). Curcuma longa and Boswellia serrata extract combination for hand osteoarthritis: an open-label pre-post trial. Pharmaceutical biology, 60(1), 2295–2299. https://doi.org/10.1080/13880209.2022.2147550
[8] Mariano, A., Bigioni, I., Mattioli, R., Di Sotto, A., Leopizzi, M., Garzoli, S., Mariani, P. F., Dalla Vedova, P., Ammendola, S., & Scotto d'Abusco, A. (2022). Harpagophytum procumbens Root Extract Mediates Anti-Inflammatory Effects in Osteoarthritis Synoviocytes through CB2 Activation. Pharmaceuticals (Basel, Switzerland), 15(4), 457. https://doi.org/10.3390/ph15040457
Shall we talk?
Contact us
Do you have any doubts or queries, or do you simply need to arrange a meeting with us? Contact us through this simple form, we will answer you as soon as possible.
The personal data contained in the consultation will be processed by BIOCAN PET'S LABORATORIES S.L. and incorporated into the CONTACTS processing activity, the purpose of which is to deal with your applications, requests or queries received from the website, by e-mail or telephone. To respond to your request and follow up on it. The legitimacy of the treatment is your consent. Your data will not be passed on to third parties. You have the right to access, rectify and delete your data, as well as other rights as explained in our privacy policy: https://www.adelopd.com/privacidad/biocan-pets-laboratories
Forgot Password